MARLY GOTTI

#### Welcome

Thank you for stopping by. Here you may find a little bit about me like publications, presentations, etc. I am a Senior Data Scientist at Biogen and a mathematician by training. I am a former intern at RStudio, where I worked with Max Kuhn developing the applicable modeling R package ッ. I enjoy the pure flavor of researching mixed with the applied nature of developing applications.

Resume

#### Selected Work Experience

##### Senior Data Scientist ⋯ 2019 Research and Development, Biogen Inc., Cambridge, MA (Current)
Lead analytical programming activities pertaining to biomarker data, clinical data, genomic data and other types of data analysis outside the typical analysis required for a clinical study report. Produce statistical specifications including but not limited to analysis datasets, simulations, statistical modeling, integration of biomarker analyses with interpretation, and contribution to abstracts and papers. Develop/maintain analytical clinical tools involving the R shiny package and/or other statistical methods in support of enrollment into clinical trials of neurological diseases.

Some of the statistical tools developed and/or contributed:
• SPARK
Interactive statistical tool to further the SPARK clinical research study that investigates the effectiveness of BIIB054, a potential drug to treat Parkinson's disease.
• tidyCDISC
Application to facilitate the creation of custom tables and figures from ADaM datasets (GitHub link: tidyCDISC).
• Risk Assessment
Interactive web application that provides a front end for a collection of metrics for R packages via the riskmetric package. It includes visualizations and comparison metrics. The app is aimed to help in the validation of R packages in the context of regulated industries (GitHub link: Risk Assessment).

##### RStudio Internship ⋯ Summer 2019 RStudio, Boston, MA
Project: Develop a modeling package (applicable) in R to demonstrate different methods to measure how much a new data point is an extrapolation from the original data. This project builds on applicability domain methods from computational chemistry to create functions that can be included in a dplyr pipeline to perform statistical checks on data in production; Mentor: Max Kuhn (RStudio Summer Interns).

##### Application Software Developer Analyst ⋯ 2017-2019 University of Florida, CTSI, FL
Work as part of a research support unit specializing in the science of information, in particular, supporting research at all stages with services such as data cleaning, collection, and analysis using R; software (modules) extensions for REDCap using PHP/Python/Javascript; software deployment and maintenance for WebCAMP; local software testing using Vagrant/Docker; Linux servers maintenance (CTSIT homepage).

##### Researcher ⋯ 2015 & 2013 University of Hawai'i at Hilo, HI
Conducted research in factorization theory as an undergraduate student and returned to the program two years later to guide/instruct a team of undergraduate students throughout the research process. Presented the findings of these two summers at the Joint Mathematics Meetings of January 2014 and 2016.

For the complete work experience, please refer to the Resume.

#### Selected Presentations

Conference:   rstudio::global(2021)
Presenting:   "Risk Assessment Tools: R Validation Hub Initiatives" (Workshop Site)
Recorded Video:   RStudio - R in Pharma Session

Conference:   R/Pharma - 2020
Workshop:   "Implementing a Risk-based Approach to R Validation" (Workshop Site)
Cohost:   Andy Nicholls

Conference:   International Conference on Mathematics and Statistics - 2020
Location:   American University of Sharjah, Sharjah, UAE
Presenting:   "When is a Puiseux Monoid Atomic?" (link)

Research Retreat:   NSF-AGEP Research Exchange Retreat - 2019
Location:   Stanford University, Stanford, CA
Presenting:   "Applicability Domain in Data Science" (link)

Conference:   R/Pharma - 2019
Location:   Harvard University, Cambridge, MA
Presenting:   "This one is not like the others: Applicability Domain methods" (link)

Conference:   AMS Joint Central and Western Sectional Meeting: "Factorization and arithmetic properties of integral domains and monoids" - 2019
Location:   University of Hawaii at Manoa, Honolulu, HI
Presenting:   "Cyclic rational semirings"

Conference:   INdAM meeting: International meeting on numerical semigroups - 2018
Location:   Cortona, Italy
Presenting:   "On the Molecules of Puiseux Monoids"

Conference:   MSRI Infinite Possibilities Conference - 2018
Location:   Howard University, Washington, DC
Presenting:   "On the Atomicity of Monotone Puiseux Monoids"

Conference:   Joint Mathematics Meetings - 2016
Location:   Washington State Convention Center, Seattle, WA
Presenting:   "On the Catenary Degree of Numerical Monoids Generated by a Generalized Arithmetic Sequence"

For the full list of presentations, please refer to the Resume.

#### Selected Research Papers

1. Atomicity and boundedness of monotone Puiseux monoids with F. Gotti, Semigroup Forum, 96(3), pp. 536–552, 2017, doi:10.1007/s00233-017-9899-9

2. On the local k-elasticities of Puiseux monoids, International Journal of Algebra and Computation, 29(01), pp. 147-158, 2019, doi:10.1142/S0218196718500662

3. How do elements really factor in $Z[\sqrt{-5}]$? with S. T. Chapman and F. Gotti, In: Advances in Commutative Algebra, pp. 171-195, 2019, Eds. A. Badawi and J. Coykendall, Springer Trends in Mathematics, Birkhäuser, Singapore, doi:10.1007/978-981-13-7028-1

4. On the molecules of numerical semigroups, Puiseux monoids, and Puiseux algebras with F. Gotti, Numerical Semigroups (Eds. V. Barucci, S. T. Chapman, M. D'Anna, and R. Fröberg), Springer INdAM Series, Vol. 40, Switzerland, 2020, arXiv:1702.08270

5. Factorization invariants of Puiseux monoids generated by geometric sequences with S. T. Chapman and F. Gotti, Communications in Algebra, Vol. 48 (2020) 380–396, doi:10.1080/00927872.2019.1646269

6.Atomicity and density of Puiseux monoids with M. Bras-Amoros, Communications in Algebra, Vol. 49 (2021) 1560-1570, doi:10.1080/00927872.2020.1840574

For the full list of research papers, please refer to the Resume.

#### Teaching

Student Assistant - Spring 2012
MAS2202 - Intro. to Number Theory
Santa Fe College, FL

Teaching Assistant - Fall 2014
MAC2311 - Calculus
University of Florida, FL

Teaching Assistant - Spring 2015
MAC2311 - Calculus
University of Florida, FL

Adjunct Assist. Prof. - Summer 2016
MAC1105 - College Algebra
Santa Fe College, FL